The skin is comprised of two main layers: the epidermis, which is the outer layer, and the dermis which placed at the middle layer of the skin under the epidermis. Collagen and elastin are structural proteins attached to the surface of the skin that is present in the dermis. The appearance of wrinkles occurs during the natural aging process. The reason for such alteration is because the body produces little collagen, and as a result for some people seeing wrinkled lines may not be pleasant. There is no surprise that many people are extremely sensitive and protective of the liveliness of their skin, especially their facial skin. Furthermore, age increase and dryness of the skin can contribute to the appearance of wrinkles.
Following dryness of the skin, the rate of cellular metabolism decreases and adequate moisture will not be created in the skin. Therefore, old and worn cells are replaced at a slower pace, and collagen and elastin, which prevent the occurrence of wrinkles, will no longer be formed on the skin.
What collagen does for the skin is that it gives elasticity to the skin, which makes it to remain and look smooth. As the levels of these proteins decrease, the firmness and strength of the skin decreases as well. As a result, the skin becomes loose and sagging, and wrinkles appear. Since it is not possible to stop the aging process, and on the other hand, the available products and methods, including creams, lotions, Botox injections, filler injections, and finally surgical procedures, are considered to be invasive, the need for new therapeutic techniques, such as cell therapy is growing rapidly.